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The Hydrogen Medicine

The hydrogen Medicine in
History & Research
In the past 200 years, only 3 research were done on hydrogen gas till 2007, as mentioned below:
  • The first paper was published by Pilcher in 1888. They used Hydrogen to blow into the gastrointestinal tract to locate visceral damage and avoid unnecessary surgery. Read More

  • The second paper was from Dole, et al, in 1975 who reported that hydrogen can inhibit cancer cells. Read More

  • In 2001, Gharib, et al, published an article who reported the anti-inflammatory properties of Hydrogen Read More
However it was in 2007, when the research by Ohsawa aroused world’s attention towards the antioxidant capacity and therapeutic effect of hydrogen on Cerebral Ischemia. This was a pioneering study that demonstrated the role of hydrogen in reducing free radicals

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The Biological Effects of Molecular Hydrogen

Antioxidant Effect
The antioxidant advantages of H2 gas includes:
  • Its high bio membrane penetration and intracellular diffusion capability which enable it to reach subcellular compartments like mitochondria; and
  • Selectively scavenging the deleterious hydroxyl radical while preserving other important reactive oxygen and nitrogen species for normal signalling regulation.
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Anti-Inflammatory Effect
Molecular hydrogen reacts with the hydroxyl radical, a highly cytotoxic species produced in inflamed tissues. It has been suggested therefore to use gaseous hydrogen in a new anti-inflammatory strategy.
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  • Anti-Apoptosis with Cytoprotection

  • Modulation of Signal Transduction

  • Maintenance of Mitochondrial Function

  • Immunomodulatory Effect